A Diffuse Optical Spectroscopy's Time Domain Optical Molecular system, non-invasive SoftScan® delivers pathophysiological changes + functional data at molecular level before they can be anatomically seen: Detects much earlier lesions and characterizes tissue without recourse to biopsy - Allows prediction of chemoresponse before treatment initiation - Earliest monitoring of therapeutic efficacy/non-efficacy of treatment administered to patient - Real time non-invasive "soft" customization of breast cancer treatments. Applicable to other body parts and diseases.