The Japan Science and Technology Agency (JST) is one of the core institutions responsible for the implementation of science and technology policy in Japan, including the government's Science and Technology Basic Plan. From knowledge creation—the wellspring of innovation—to ensuring that the fruits of research are shared with society and Japan's citizens, JST undertakes its mission in a comprehensive manner. JST also works to provide a sound infrastructure of science and technology information and raise awareness and understanding of science and technology-related issues in Japan.RISTEX•RISTEX is a part of Japan Science and Technology Agency (JST) that primarily functions as a funding agency with a think tank-like capacity.•While collaborating with a wide variety of stakeholders, RISTEX aims to bolster social systems and mechanisms which generate outcomes valuable to the public.•In doing so, RISTEX's research and development (R&D) produce and utilize "know-how"​ such as evidence-based,scientifically-grounded data, methods, theories, models, policy proposals and tools-that contribute to solving social problems.