Pioneer Research is developing cutting-edge, targeted treatment using microProteins for clinical use, based on a deep understanding of chromatin dynamic and transcriptional regulation through pioneer transcription factors. Through functional analysis, knowledge based design and rigorous experimental validation, Pioneer Reseach´s microProtein treatment can be tailored to enforce a beneficial transcription profile for diseases driven by dysregulated pioneer transcription factors and master regulators. Around 50% of diseases and syndromes are caused by, at least in part, dysregulated master regulators and pioneer transcription factors and the Pioneer Research platform has the potential to address many disease areas with a high unmet medical need, such as cancer.